The isolation and serology of the "FSA" Brucella melitensis Rev. 1 mutant in a flock of sheep

A flock of sheep, known to be infected with the "FSA" mutant of Brucella melitensis Rev. 1, was\ud examined serologically and bacteriologically to detennine whether any relationship existed which would help in\ud the control of this infection in the field. An attempt was also made to determine whether vertical transmission\ud occurred. Twenty-one out of 62 sheep were bacteriologically positive. The best organs for isolation were the\ud udder, supramammary lymphnodes and uterus. No significant relationship could be shown between the complement\ud fixation test and bacterial isolation. The absence of any relationship between serological and bacteriological\ud results agrees with a short-lived infection. None of the 24 lambs sacrificed at 5 months showed either\ud serological reactions or were bacteriologically positive, thus no vertical transmission could be shown